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mTORC1 and JNK coordinate phosphorylation of the p70S6K1 autoinhibitory domain in skeletal muscle following functional overloading

The present project was designed to investigate phosphorylation of p70S6K1 in an animal model of skeletal muscle overload. Within 24 h of male Sprague-Dawley rats undergoing unilateral tenotomy to induce functional overloading of the plantaris muscle, phosphorylation of the Thr(389) and Thr(421)/Ser...

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Detalles Bibliográficos
Main Authors: Martin, Tony D., Dennis, Michael D., Gordon, Bradley S., Kimball, Scot R., Jefferson, Leonard S.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059989/
https://ncbi.nlm.nih.gov/pubmed/24801387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00064.2014
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