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The mTORC1 signaling repressors REDD1/2 are rapidly induced and activation of p70S6K1 by leucine is defective in skeletal muscle of an immobilized rat hindlimb

Limb immobilization, limb suspension, and bed rest cause substantial loss of skeletal muscle mass, a phenomenon termed disuse atrophy. To acquire new knowledge that will assist in the development of therapeutic strategies for minimizing disuse atrophy, the present study was undertaken with the aim o...

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Detalhes bibliográficos
Main Authors: Kelleher, Andrew R., Kimball, Scot R., Dennis, Michael D., Schilder, Rudolf J., Jefferson, Leonard S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543567/
https://ncbi.nlm.nih.gov/pubmed/23193052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00409.2012
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