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SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts
Ischemia-reperfusion (IR) injury is significantly worse in aged hearts, but the underlying mechanisms are poorly understood. Age-related damage to mitochondria may be a critical feature, which manifests in an exacerbation of IR injury. Silent information regulator of transcription 3 (SIRT3), the maj...
Gorde:
| Egile Nagusiak: | , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059981/ https://ncbi.nlm.nih.gov/pubmed/24748594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00027.2014 |
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