CD59a Deficiency Exacerbates Ischemia-Reperfusion Injury in Mice

The terminal complement components C5a and the membrane attack complex are involved in the pathogenesis of ischemia-reperfusion injury in many organs. CD59 is the major regulator of membrane attack complex formation. Mice deficient in the Cd59a gene (mCd59a−/−) were used to investigate the role of C...

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Main Authors: Turnberg, Daniel, Botto, Marina, Lewis, Margarita, Zhou, Wuding, Sacks, Steven H., Morgan, B. Paul, Walport, Mark J., Cook, H. Terence
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2004
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618586/
https://ncbi.nlm.nih.gov/pubmed/15331407
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