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Different mechanisms of mitochondrial proton leak in ischaemia/reperfusion injury and preconditioning: implications for pathology and cardioprotection

The mechanisms of mitochondrial proton (H(+)) leak under various pathophysiological conditions are poorly understood. In the present study it was hypothesized that different mechanisms underlie H(+) leak in cardiac IR (ischaemia/reperfusion) injury and IPC (ischaemic preconditioning). Potential H(+)...

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Détails bibliographiques
Auteurs principaux: Nadtochiy, Sergiy M., Tompkins, Andrew J., Brookes, Paul S.
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462692/
https://ncbi.nlm.nih.gov/pubmed/16436046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051927
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