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Proteasome proteolysis supports stimulated platelet function and thrombosis

OBJECTIVE: Proteasome inhibitors are in use to treat hematologic cancers, but also reduce thrombosis. Whether the proteasome participates in platelet activation or function is opaque since little is known of the proteasome in these terminally differentiated cells. APPROACH AND RESULTS: Platelets dis...

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Detalhes bibliográficos
Main Authors: Gupta, Nilaksh, Li, Wei, Willard, Belinda, Silverstein, Roy L., McIntyre, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059534/
https://ncbi.nlm.nih.gov/pubmed/24177323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302116
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