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Deubiquitinases modulate platelet proteome ubiquitination, aggregation, and thrombosis
OBJECTIVE: Platelets express a functional ubiquitin-proteasome system. Mass spectrometry shows platelets contain several deubiquitinases, but whether these are functional, modulate the proteome, or affect platelet reactivity are unknown. APPROACH AND RESULTS: Platelet lysates contained ubiquitin-pro...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662625/ https://ncbi.nlm.nih.gov/pubmed/26471267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306054 |
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