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Exosome poly-ubiquitin inhibits platelet activation, downregulates CD36, and inhibits pro-atherothombotic cellular functions

INTRODUCTION: Activated platelets shed microparticles from plasma membranes, but also release smaller exosomes from internal compartments. While microparticles participate in athero-thrombosis, little is known of exosomes in this process. MATERIALS & METHODS: Ex vivo biochemical experiments with...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Srikanthan, Sowmya, Li, Wei, Silverstein, Roy L., McIntyre, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229405/
https://ncbi.nlm.nih.gov/pubmed/25163645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12712
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