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On the Observation of Discrete Fluorine NMR Spectra for Uridine 5′-β,γ-Fluoromethylenetriphosphate Diastereomers at Basic pH

[Image: see text] Jakeman et al. recently reported the inability to distinguish the diastereomers of uridine 5′-β,γ-fluoromethylenetriphosphate (β,γ-CHF-UTP, 1) by (19)F NMR under conditions we previously prescribed for the resolution of the corresponding β,γ-CHF-dGTP spectra, stating further that 1...

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Main Authors: Hwang, Candy S., Kashemirov, Boris A., McKenna, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059216/
https://ncbi.nlm.nih.gov/pubmed/24819695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500452b
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