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α-Allyl-α-aryl α-Amino Esters in the Asymmetric Synthesis of Acyclic and Cyclic Amino Acid Derivatives by Alkene Metathesis

[Image: see text] Allylating agents were explored for the asymmetric synthesis of α-allyl-α-aryl α-amino acids by tandem N-alkylation/π-allylation. Cross-metathesis of the tandem product was developed to provide allylic diversity not afforded in the parent reaction; the synthesis of homotyrosine and...

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Detalhes bibliográficos
Main Authors: Curto, John M., Kozlowski, Marisa C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059215/
https://ncbi.nlm.nih.gov/pubmed/24828423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500707t
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