FRNK Inhibition of Focal Adhesion Kinase–Dependent Signaling and Migration in Vascular Smooth Muscle Cells

OBJECTIVE: To examine whether interference with FRNK targeting to focal adhesions (FAs) affects its inhibitory activity and tyrosine phosphorylation. METHODS AND RESULTS: Focal adhesion kinase and its autonomously expressed C-terminal inhibitor, focal adhesion kinase–related nonkinase (FRNK), regula...

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Autores principales: Koshman, Yevgeniya E., Kim, Taehoon, Chu, Miensheng, Engman, Steven J., Iyengar, Rekha, Robia, Seth L., Samarel, Allen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058887/
https://ncbi.nlm.nih.gov/pubmed/20705914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.212761
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