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Defective secretory-protein mRNAs take the RAPP

Secretory proteins destined for the lumen of the endoplasmic reticulum are key regulators of cellular functions and are thus subject to several levels of quality control. A recent study finds that the earliest step in secretory protein biogenesis, i.e. binding of the signal recognition particle to t...

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Hlavní autoři: Maximilian Wei-Lin, Popp, Maquat, Lynne E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4058773/
https://ncbi.nlm.nih.gov/pubmed/24602384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.02.001
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