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Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells
Recently, loss of beta cell-specific traits has been proposed as an early cause of beta cell failure in diabetes. However, the molecular mechanisms that underlie this loss of beta cell features remain unclear. Here, we identify an Nkx6.1-controlled gene regulatory network as essential for maintainin...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4058003/ https://ncbi.nlm.nih.gov/pubmed/24035389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.08.010 |
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