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Distinct Regulation of Hepatic Nuclear Factor 1α by NKX6.1 in Pancreatic Beta Cells

Hepatic nuclear factor 1α (HNF1α) is a key regulator of development and function in pancreatic beta cells and is specifically involved in regulation of glycolysis and glucose-stimulated insulin secretion. Abnormal expression of HNF1α leads to development of MODY3 (maturity-onset diabetes of the youn...

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Bibliografiske detaljer
Main Authors: Donelan, William, Koya, Vijay, Li, Shi-Wu, Yang, Li-Jun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852957/
https://ncbi.nlm.nih.gov/pubmed/20106981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064238
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