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Distinct Regulation of Hepatic Nuclear Factor 1α by NKX6.1 in Pancreatic Beta Cells
Hepatic nuclear factor 1α (HNF1α) is a key regulator of development and function in pancreatic beta cells and is specifically involved in regulation of glycolysis and glucose-stimulated insulin secretion. Abnormal expression of HNF1α leads to development of MODY3 (maturity-onset diabetes of the youn...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852957/ https://ncbi.nlm.nih.gov/pubmed/20106981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.064238 |
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