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Differentiation of human pluripotent stem cells into two distinct NKX6.1 populations of pancreatic progenitors
BACKGROUND: The expression of a specific combination of transcription factors (TFs) in the multipotent progenitor cells (MPCs) is critical for determining pancreatic cell fate. NKX6.1 expression in PDX1(+) MPCs is required for functional β cell generation. We have recently demonstrated the generatio...
Gespeichert in:
| Veröffentlicht in: | Stem Cell Res Ther |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5883581/ https://ncbi.nlm.nih.gov/pubmed/29615106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0834-0 |
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