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Nkx6.1 Controls a Gene Regulatory Network Required for Establishing and Maintaining Pancreatic Beta Cell Identity

All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell lineage have remained largely elusive. Such knowledge would improve our ability to correctl...

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Detalhes bibliográficos
Main Authors: Schaffer, Ashleigh E., Taylor, Brandon L., Benthuysen, Jacqueline R., Liu, Jingxuan, Thorel, Fabrizio, Yuan, Weiping, Jiao, Yang, Kaestner, Klaus H., Herrera, Pedro L., Magnuson, Mark A., May, Catherine Lee, Sander, Maike
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561089/
https://ncbi.nlm.nih.gov/pubmed/23382704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003274
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