Impact of regulated secretion on anti-parasitic CD8 T cell responses

CD8 T cells play a key role in defense against the intracellular parasite Toxoplasma but why certain CD8 responses are more potent than others is not well understood. Here, we describe a parasite antigen ROP5 that elicits a modest CD8 T cell response in genetically susceptible mice. ROP5 is secreted...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Grover, Harshita Satija, Chu, H. Hamlet, Kelly, Felice D., Yang, Soo Jung, Reese, Michael L., Blanchard, Nicolas, Gonzalez, Federico, Chan, Shiao Wei, Boothroyd, John C., Shastri, Nilabh, Robey, Ellen A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057976/
https://ncbi.nlm.nih.gov/pubmed/24857659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.031
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg