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Continuous effector T cell production in a controlled persistent infection is sustained by a proliferative subset of memory-effector hybrid phenotype
Highly functional CD8(+) effector T (Teff) cells can persist in large numbers during controlled persistent infections, as exemplified by rare HIV-infected individuals who control the virus. Here we examined the cellular mechanisms that maintain ongoing T effector responses using a mouse model for pe...
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| 發表在: | Immunity |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956557/ https://ncbi.nlm.nih.gov/pubmed/27421704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.06.013 |
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