Loading...

Homologue engagement controls meiotic DNA break number and distribution

Meiotic recombination promotes genetic diversification as well as pairing and segregation of homologous chromosomes, but the double-strand breaks (DSBs) that initiate recombination are dangerous lesions that can cause mutation or meiotic failure. How cells control DSBs to balance between beneficial...

Full description

Saved in:
Bibliographic Details
Main Authors: Thacker, Drew, Mohibullah, Neeman, Zhu, Xuan, Keeney, Scott
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057310/
https://ncbi.nlm.nih.gov/pubmed/24717437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13120
Tags: Add Tag
No Tags, Be the first to tag this record!