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Homologue engagement controls meiotic DNA break number and distribution

Meiotic recombination promotes genetic diversification as well as pairing and segregation of homologous chromosomes, but the double-strand breaks (DSBs) that initiate recombination are dangerous lesions that can cause mutation or meiotic failure. How cells control DSBs to balance between beneficial...

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Bibliografiske detaljer
Main Authors: Thacker, Drew, Mohibullah, Neeman, Zhu, Xuan, Keeney, Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057310/
https://ncbi.nlm.nih.gov/pubmed/24717437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13120
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