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Numerical and spatial patterning of yeast meiotic DNA breaks by Tel1

The Spo11-generated double-strand breaks (DSBs) that initiate meiotic recombination are dangerous lesions that can disrupt genome integrity, so meiotic cells regulate their number, timing, and distribution. Mechanisms of this regulation remain poorly understood. Here, we use Spo11-oligonucleotide co...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Mohibullah, Neeman, Keeney, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287233/
https://ncbi.nlm.nih.gov/pubmed/27923845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.213587.116
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