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Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways
Organofluorines represent a rapidly expanding proportion of molecules used in pharmaceuticals, diagnostics, agrochemicals, and materials. Despite the prevalence of fluorine in synthetic compounds, the known biological scope is limited to a single pathway that produces fluoroacetate. Here, we demonst...
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| Main Authors: | , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4057101/ https://ncbi.nlm.nih.gov/pubmed/24009388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1242345 |
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