DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer

Simultaneous interrogation of tumor genomes and transcriptomes is underway in unprecedented global efforts. Yet, despite the essential need to separate driver mutations modulating gene expression networks from transcriptionally inert passenger mutations, robust computational methods to ascertain the...

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Detalhes bibliográficos
Main Authors: Bashashati, Ali, Haffari, Gholamreza, Ding, Jiarui, Ha, Gavin, Lui, Kenneth, Rosner, Jamie, Huntsman, David G, Caldas, Carlos, Aparicio, Samuel A, Shah, Sohrab P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056374/
https://ncbi.nlm.nih.gov/pubmed/23383675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-12-r124
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