Mechanical ventilation drives pneumococcal pneumonia into lung injury and sepsis in mice: protection by adrenomedullin

INTRODUCTION: Ventilator-induced lung injury (VILI) contributes to morbidity and mortality in acute respiratory distress syndrome (ARDS). Particularly pre-injured lungs are susceptible to VILI despite protective ventilation. In a previous study, the endogenous peptide adrenomedullin (AM) protected m...

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Detaylı Bibliyografya
Asıl Yazarlar: Müller-Redetzky, Holger C, Will, Daniel, Hellwig, Katharina, Kummer, Wolfgang, Tschernig, Thomas, Pfeil, Uwe, Paddenberg, Renate, Menger, Michael D, Kershaw, Olivia, Gruber, Achim D, Weissmann, Norbert, Hippenstiel, Stefan, Suttorp, Norbert, Witzenrath, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056010/
https://ncbi.nlm.nih.gov/pubmed/24731244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc13830
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