Simvastatin attenuates ventilator-induced lung injury in mice

INTRODUCTION: Mechanical ventilation (MV) is a life saving intervention in acute respiratory failure without alternative. However, particularly in pre-injured lungs, even protective ventilation strategies may evoke ventilator-induced lung injury (VILI), which is characterized by pulmonary inflammati...

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Main Authors: Müller, Holger C, Hellwig, Katharina, Rosseau, Simone, Tschernig, Thomas, Schmiedl, Andreas, Gutbier, Birgitt, Schmeck, Bernd, Hippenstiel, Stefan, Peters, Harm, Morawietz, Lars, Suttorp, Norbert, Witzenrath, Martin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945124/
https://ncbi.nlm.nih.gov/pubmed/20673352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9209
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