Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategy

The signaling lymphocytic activation molecule (SLAM) receptor-associated adaptor Ewing’s sarcoma-associated transcript-2 (EAT-2) is primarily expressed in innate immune cells including dendritic cells (DCs), macrophages and NK cells. A recent human HIV vaccine study confirmed that EAT-2 expression w...

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Autores principales: Aldhamen, Yasser A., Seregin, Sergey S., Aylsworth, Charles F., Godbehere, Sarah, Amalfitano, Andrea
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055832/
https://ncbi.nlm.nih.gov/pubmed/24374770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxt061
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