ERAP1 functions override the intrinsic selection of specific antigens as immunodominant peptides, thereby altering the potency of antigen-specific cytolytic and effector memory T-cell responses

Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a critical component of the adaptive immune system that has been shown to increase or decrease the presentation of specific peptides on MHC class I molecules. Here, we have demonstrated that ERAP1 functions are not only important during the presentat...

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Bibliografische gegevens
Gepubliceerd in:Int Immunol
Hoofdauteurs: Rastall, David P. W., Aldhamen, Yasser A., Seregin, Sergey S., Godbehere, Sarah, Amalfitano, Andrea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574741/
https://ncbi.nlm.nih.gov/pubmed/25087231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxu078
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