Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2

The signaling lymphocytic activation molecule-associated adaptor Ewing's sarcoma's-activated transcript 2 (EAT-2) is primarily expressed in dendritic cells, macrophages and natural killer cells. Including EAT-2 in a vaccination regimen enhanced innate and adaptive immune responses toward p...

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Detalhes bibliográficos
Main Authors: Aldhamen, YA, Seregin, SS, Kousa, YA, Rastall, DPW, Appledorn, DM, Godbehere, S, Schutte, BC, Amalfitano, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142478/
https://ncbi.nlm.nih.gov/pubmed/23949283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.53
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