Stimulation of Innate Immunity by In Vivo Cyclic di-GMP Synthesis Using Adenovirus

The bacterial second messenger cyclic di-GMP (c-di-GMP) stimulates inflammation by initiating innate immune cell recruitment and triggering the release of proinflammatory cytokines and chemokines. These properties make c-di-GMP a promising candidate for use as a vaccine adjuvant, and numerous studie...

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發表在:Clin Vaccine Immunol
Main Authors: Koestler, Benjamin J., Seregin, Sergey S., Rastall, David P. W., Aldhamen, Yasser A., Godbehere, Sarah, Amalfitano, Andrea, Waters, Christopher M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2014
主題:
Vaccines
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248757/
https://ncbi.nlm.nih.gov/pubmed/25230938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00471-14
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