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INHIBITION OF STRIATAL-ENRICHED TYROSINE PHOSPHATASE 61 IN THE DORSOMEDIAL STRIATUM IS SUFFICIENT TO INCREASED ETHANOL CONSUMPTION

The STriatal-Enriched protein tyrosine Phosphatase 61 (STEP(61)) inhibits the activity of the tyrosine kinase Fyn and dephosphorylates the GluN2B subunit of the NMDA receptor, whereas PKA phosphorylation of STEP(61) inhibits the activity of the phosphatase (Goebel-Goody et al. 2012). Previously, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Darcq, E., Ben Hamida, S., Wu, S., Phamluong, K., Kharazia, V., Xu, J., Lombroso, P., Ron, D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055745/
https://ncbi.nlm.nih.gov/pubmed/24588427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12701
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