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Protein Tyrosine Phosphatase α in the Dorsomedial Striatum Promotes Excessive Ethanol-Drinking Behaviors

We previously found that excessive ethanol drinking activates Fyn in the dorsomedial striatum (DMS) (Wang et al., 2010; Gibb et al., 2011). Ethanol-mediated Fyn activation in the DMS leads to the phosphorylation of the GluN2B subunit of the NMDA receptor, to the enhancement of the channel's act...

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Главные авторы: Ben Hamida, Sami, Darcq, Emmanuel, Wang, Jun, Wu, Su, Phamluong, Khanhky, Kharazia, Viktor, Ron, Dorit
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3761047/
https://ncbi.nlm.nih.gov/pubmed/24005290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1954-13.2013
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