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INHIBITION OF STRIATAL-ENRICHED TYROSINE PHOSPHATASE 61 IN THE DORSOMEDIAL STRIATUM IS SUFFICIENT TO INCREASED ETHANOL CONSUMPTION

The STriatal-Enriched protein tyrosine Phosphatase 61 (STEP(61)) inhibits the activity of the tyrosine kinase Fyn and dephosphorylates the GluN2B subunit of the NMDA receptor, whereas PKA phosphorylation of STEP(61) inhibits the activity of the phosphatase (Goebel-Goody et al. 2012). Previously, we...

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Autori principali: Darcq, E., Ben Hamida, S., Wu, S., Phamluong, K., Kharazia, V., Xu, J., Lombroso, P., Ron, D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055745/
https://ncbi.nlm.nih.gov/pubmed/24588427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12701
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