Application of Molecular Modeling to Urokinase Inhibitors Development

Urokinase-type plasminogen activator (uPA) plays an important role in the regulation of diverse physiologic and pathologic processes. Experimental research has shown that elevated uPA expression is associated with cancer progression, metastasis, and shortened survival in patients, whereas suppressio...

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Hlavní autoři: Sulimov, V. B., Katkova, E. V., Oferkin, I. V., Sulimov, A. V., Romanov, A. N., Roschin, A. I., Beloglazova, I. B., Plekhanova, O. S., Tkachuk, V. A., Sadovnichiy, V. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055159/
https://ncbi.nlm.nih.gov/pubmed/24967388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/625176
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