Application of Molecular Modeling to Urokinase Inhibitors Development

Urokinase-type plasminogen activator (uPA) plays an important role in the regulation of diverse physiologic and pathologic processes. Experimental research has shown that elevated uPA expression is associated with cancer progression, metastasis, and shortened survival in patients, whereas suppressio...

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Detalhes bibliográficos
Main Authors: Sulimov, V. B., Katkova, E. V., Oferkin, I. V., Sulimov, A. V., Romanov, A. N., Roschin, A. I., Beloglazova, I. B., Plekhanova, O. S., Tkachuk, V. A., Sadovnichiy, V. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4055159/
https://ncbi.nlm.nih.gov/pubmed/24967388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/625176
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