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PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data

PIK3CA mutations represent one of the most common genetic aberrations in breast cancer. They have been reported to be present in over one-third of cases, with enrichment in the luminal and in human epidermal growth factor receptor 2-positive subtypes. Substantial preclinical data on the oncogenic pr...

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Hlavní autoři: Zardavas, Dimitrios, Phillips, Wayne A, Loi, Sherene
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054885/
https://ncbi.nlm.nih.gov/pubmed/25192370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3605
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