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PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data
PIK3CA mutations represent one of the most common genetic aberrations in breast cancer. They have been reported to be present in over one-third of cases, with enrichment in the luminal and in human epidermal growth factor receptor 2-positive subtypes. Substantial preclinical data on the oncogenic pr...
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Main Authors: | , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
BioMed Central
2014
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054885/ https://ncbi.nlm.nih.gov/pubmed/25192370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3605 |
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