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PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data
PIK3CA mutations represent one of the most common genetic aberrations in breast cancer. They have been reported to be present in over one-third of cases, with enrichment in the luminal and in human epidermal growth factor receptor 2-positive subtypes. Substantial preclinical data on the oncogenic pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054885/ https://ncbi.nlm.nih.gov/pubmed/25192370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3605 |
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