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Mouse Models for Exploring the Biological Consequences and Clinical Significance of PIK3CA Mutations

The phosphatidylinositol 3-kinase (PI3K) pathway is involved in a myriad of cellular signalling pathways that regulate cell growth, metabolism, proliferation and survival. As a result, alterations in the PI3K pathway are frequently associated with human cancers. Indeed, PIK3CA—the gene encoding the...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Mitchell, Camilla B., Phillips, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523081/
https://ncbi.nlm.nih.gov/pubmed/31018529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9040158
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