Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions

When telomeres become critically short DNA damage response factors are recruited at chromosome ends initiating a cellular response to DNA damage. We performed Proteomic Isolation of Chromatin fragments (PICh) to define changes in chromatin composition that occur upon onset of acute telomere dysfunct...

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Hauptverfasser: Bartocci, Cristina, Diedrich, Jolene K., Ouzounov, Iliana, Li, Julia, Piunti, Andrea, Pasini, Diego, Yates, John R., Denchi, Eros Lazzerini
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054697/
https://ncbi.nlm.nih.gov/pubmed/24813883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.002
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