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Isolation of chromatin from dysfunctional telomeres reveals an important role for Ring1b in NHEJ-mediated chromosome fusions
When telomeres become critically short DNA damage response factors are recruited at chromosome ends initiating a cellular response to DNA damage. We performed Proteomic Isolation of Chromatin fragments (PICh) to define changes in chromatin composition that occur upon onset of acute telomere dysfunct...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054697/ https://ncbi.nlm.nih.gov/pubmed/24813883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.04.002 |
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