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Ex vivo Analysis of Resident Hepatic Pro-inflammatory CD1d-reactive T cells & Hepatocyte Surface CD1d Expression in Hepatitis C

Hepatic CD1d-restricted and natural killer T cell populations are heterogeneous. Classical ‘Type 1’ α-galactosylceramide-reactive CD1d-restricted T cells express ‘invariant’ TCRα (‘iNKT’). iNKT dominating rodent liver are implicated in inflammation, including in hepatitis models. Low levels of iNKT...

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Detalhes bibliográficos
Main Authors: Yanagisawa, Kazuhiko, Yue, Simon, van der Vliet, Hans J., Wang, RuoJie, Alatrakchi, Nadia, Golden-Mason, Lucy, Schuppan, Detlef, Koziel, Margaret J., Rosen, Hugo R., Exley, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054599/
https://ncbi.nlm.nih.gov/pubmed/23808994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvh.12081
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