Hepatitis C Virus (HCV)-Specific CD8(+) Cells Produce Transforming Growth Factor β That Can Suppress HCV-Specific T-Cell Responses

Hepatitis C virus (HCV)-specific T-cell responses are rarely detected in peripheral blood, especially in the presence of human immunodeficiency virus (HIV) coinfection. Based on recent evidence that T-regulatory cells may be increased in chronic HCV, we hypothesized that functional blockade of regul...

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Detalhes bibliográficos
Main Authors: Alatrakchi, Nadia, Graham, Camilla S., van der Vliet, Hans J. J., Sherman, Kenneth E., Exley, Mark A., Koziel, Margaret James
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900307/
https://ncbi.nlm.nih.gov/pubmed/17376924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02202-06
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