Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepatitis C Virus (HCV)-Specific CD8(+) T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses

T cell responses play a critical role in controlling or clearing viruses. Therefore, strategies to prevent or treat infections include boosting T cell responses. T cells specific for various pathogens have been reported in unexposed individuals and an influence of such cells on the response toward v...

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Veröffentlicht in:J Virol
Hauptverfasser: Zhang, Shihong, Bakshi, Rakesh K., Suneetha, Pothakamuri Venkata, Fytili, Paraskevi, Antunes, Dinler A., Vieira, Gustavo F., Jacobs, Roland, Klade, Christoph S., Manns, Michael P., Kraft, Anke R. M., Wedemeyer, Heiner, Schlaphoff, Verena, Cornberg, Markus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524240/
https://ncbi.nlm.nih.gov/pubmed/26041301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00539-15
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