Frequency, Private Specificity, and Cross-Reactivity of Preexisting Hepatitis C Virus (HCV)-Specific CD8(+) T Cells in HCV-Seronegative Individuals: Implications for Vaccine Responses

T cell responses play a critical role in controlling or clearing viruses. Therefore, strategies to prevent or treat infections include boosting T cell responses. T cells specific for various pathogens have been reported in unexposed individuals and an influence of such cells on the response toward v...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zhang, Shihong, Bakshi, Rakesh K., Suneetha, Pothakamuri Venkata, Fytili, Paraskevi, Antunes, Dinler A., Vieira, Gustavo F., Jacobs, Roland, Klade, Christoph S., Manns, Michael P., Kraft, Anke R. M., Wedemeyer, Heiner, Schlaphoff, Verena, Cornberg, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524240/
https://ncbi.nlm.nih.gov/pubmed/26041301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00539-15
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