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DIRECT CD1d-MEDIATED STIMULATION OF APC IL-12 PRODUCTION AND PROTECTIVE IMMUNE RESPONSE TO VIRUS INFECTION In Vivo

CD1d-restricted ‘NKT’ rapidly stimulate innate and adaptive immunity through production of Th1 and/or Th2 cytokines and induction of CD1d(+) antigen-presenting cell (APC) maturation. However, therapeutic exploitation of NKT has been hampered by their paucity and defects in human disease. NKT:APC int...

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Detalhes bibliográficos
Main Authors: Yue, Simon C., Nowak, Michael, Shaulov-Kask, Angela, Wang, RuoJie, Yue, Dominic, Balk, Steven P., Exley, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967442/
https://ncbi.nlm.nih.gov/pubmed/19949077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800924
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