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HIV-1 Protease-Substrate Coevolution in Nelfinavir Resistance
Resistance to various human immunodeficiency virus type 1 (HIV-1) protease inhibitors (PIs) challenges the effectiveness of therapies in treating HIV-1-infected individuals and AIDS patients. The virus accumulates mutations within the protease (PR) that render the PIs less potent. Occasionally, Gag...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054462/ https://ncbi.nlm.nih.gov/pubmed/24719428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00266-14 |
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