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Mechanism and Significance of Cell Type-Dependent Neutralization of Flaviviruses

The production of neutralizing antibodies (NAbs) is a correlate of protection for many human vaccines, including currently licensed vaccines against flaviviruses. NAbs are typically measured using a plaque reduction neutralization test (PRNT). Despite its extensive use, parameters that impact the pe...

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Detalhes bibliográficos
Main Authors: Mukherjee, Swati, Dowd, Kimberly A., Manhart, Carolyn J., Ledgerwood, Julie E., Durbin, Anna P., Whitehead, Stephen S., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054442/
https://ncbi.nlm.nih.gov/pubmed/24741083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03690-13
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