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Combined Effects of the Structural Heterogeneity and Dynamics of Flaviviruses on Antibody Recognition

Flaviviruses are thought to sample an ensemble of structures at equilibrium. One consequence of a structurally dynamic virion is the observed time-dependent increases in neutralization sensitivity that can occur after prolonged incubation with antibody. Differences in how virus strains “breathe” may...

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Detalhes bibliográficos
Main Authors: Dowd, Kimberly A., Mukherjee, Swati, Kuhn, Richard J., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178732/
https://ncbi.nlm.nih.gov/pubmed/25078693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01140-14
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