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Impact of viral attachment factor expression on antibody-mediated neutralization of flaviviruses

Neutralization of flaviviruses requires engagement of the virion by antibodies with a stoichiometry that exceeds a required threshold. Factors that modulate the number of antibodies bound to an individual virion when it contacts target cells impact neutralization potency. However, the contribution o...

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Detalhes bibliográficos
Main Authors: Obara, Christopher J., Dowd, Kimberly A., Ledgerwood, Julie E., Pierson, Theodore C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601793/
https://ncbi.nlm.nih.gov/pubmed/23312596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.11.016
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